2024.05.14
【論文】WRH津島 悟特任准教授と鷹尾康一朗准教授の共著論文がChemical Communicationsの表紙を飾りました。
“Towards tailoring hydrophobic interaction with uranyl(vi) oxygen for C–H activation”
＜Article information＞
DOI https://doi.org/10.1039/D4CC01030B
＜要旨＞
Bovine serum albumin (BSA) has a uranyl(VI) binding hotspot where uranium is tightly bound by three carboxylates. Uranyl oxygen is “soaked” into the hydrophobic core of BSA. Isopropyl hydrogen of Val is trapped near UO22+ and upon photoexcitation, C–H bond cleavage is initiated. A unique hydrophobic contact with “yl”-oxygen, as observed here, can be used to induce C–H activation.
＜関連リンク＞
– Chemical Communications Issue 36, 2024 cover
– World Research Hub (WRH) Program
–鷹尾 研究室