Dr. Hisakazu Mihara, Dr. Hiroshi Tsutsumi and the group have set out to harness the potential of self-assembling peptides (SAPs) in intracellular spaces. They present a de novo designed peptide, Y15, which displays a strong tendency to assemble in cellular environments. The addition of Y15-tagged bioactive proteins can functionalize these assemblies, enhancing their utility and relevance by leaps and bounds.

Title of original paper : Intracellular artificial supramolecules based on de novo designed Y15 peptides

DOI : 10.1038/s41467-021-23794-6

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