Dr. Hiroshi Kimura  (Cell Biology Center)

A genetically encoded “live-cell” probe designed by researchers from Tokyo Tech has been able to identify phosphorylated Ser2 in the enzyme RNA polymerase II, subsequently identifying sites of the elongation phase of active transcription in living cells. This probe could be used to specifically image transcription elongation in real time in living animals, furthering gene regulation research by leaps and bounds.

Title of original paper: “Live Imaging of Transcription Sites Using an Elongating RNA Polymerase II-specific Probe”

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