材料・デバイス研究
James M. Lisy
特任教授
分子クラスターの振動分光
略歴
Professor James M. Lisy received his B.S. degree from Iowa State University in 1974 and his Ph.D. from Harvard University in 1979. He joined the faculty at Illinois in 1981 and spent his career investigating intermolecular interactions in neutral and charged molecular clusters. After 30 years, he elected to take early retirement, and spent 9 months at the Ruhr University - Bochum as an Alexander von Humboldt Fellow. He then moved to the National Science Foundation in Arlington, VA, where he served as a program officer for over 5 years. During that time, he also was a visiting or guest professor in France, Japan, and Denmark. He currently maintains active collaborations in these countries as well as Germany, and resides in the Bay Area of California. Selected Awards: Fellow-JSPS 2014, 1996; Alexander von Humboldt Research Award 2011; Fellow-American Physical Society 2001; Wilsmore Fellow-University of Melbourne 2004-5.
WRHIへの期待
Participating in research within the WRHI at the Institute for Innovative Research, provides me with state-of-the-art equipment to probe intermolecular interactions using mass-selective spectroscopy. These facilities have enabled me to extent my investigations in new and exciting directions.
研究プロジェクト
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溶媒和イオンのコンフォーメーション選択的解離、サイズ特異的な分子間相互作用の発見、イオンクラスター 形成に対するMDシミュレーション、高エネルギーコンフォマーと高度に非調和的な分子種を解析するためのDFT-MD非調和振動計算とカップルした振動分光
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Elucidating the Mechanism of Size-Selectivity in Ion Channels.
Using specific peptide sequences, the binding properties of potassium and sodium ions are compared with structural details provided by mass-
selective infrared spectroscopy. The differences between the two ions provides insight into the remarkable selectivity of potassium ion channels in biological systems.
Periods: January 2018 to present.
Funding Sources: KAKENHI (JP205104008) on innovative area (2503), KAKENHI (JP18H01938) of JSPS, and the Cooperative Research Program of the ‘‘Network Joint Research Center for Materials and Devices’’ from the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan. World Research Hub Initiative and the Institute of Innovative Research (specially appointed professorship).
Members: Prof. Masaaki Fujii, Prof. Shun-ichi Ishiuchi, Mr. Yuta Sazaki.Ion Channels Infrared Spectroscopy Cluster Ions
1981-2011 |
イリノイ大学教授 |
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2011-現在 |
イリノイ大学名誉教授 |
2012-2017 |
アメリカ国立科学財団(NSF)プログラムディレクター
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2017-現在 |
東京工業大学科学技術創成研究院 特任教授 |
2014 |
1996 JSPSフェロー |
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2011 |
アレキサンダー・フンボルト賞 |
2001 |
米国物理学会フェロー |
2004-5 |
メルボルン大学ウィルスモア・フェロー |
2019 |
Ion-peptide interactions between alkali metal ions and a termini-protected dipeptide:Modeling a portion of the selectivity filter in K+ channels. |
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2018 |
Fundamental FH-stretching transition frequencies and oscillator strengths in hydrogen bonded FH complexes, Gas-Phase Ion Spectroscopy of Congo Red Dianions and Their Complexes with Betaine, Influence of argon and D2 tagging on the hydrogen bond network in Cs+(H2O)3 ; Kinetic trapping below 40 K,
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2015 |
Modeling the CH Stretch Vibrational Spectroscopy of M+[Cyclohexane] (M = Li, Na, and K) Ions, Sibert, E.L., Tabor, D.P., Lisy, J.M., Journal of Physical Chemistry A 119(41), pp. 10293-10299 (2015) |
2014 |
O-H anharmonic vibrational motions in Cl-⋯(CH 3OH)1-2 ionic clusters. Combined IRPD experiments and AIMD simulations, Beck, J.P., Cimas, A., Lisy, J.M., Gaigeot, M.-P. Spectrochimica Acta – Part A: Molecular and Biomolecular Spectroscopy 119, pp. 12-17 (2014) |
2011 |
Revisiting Li+(H2O)3-4Ar1 clusters: Evidence of high-energy conformers from infrared spectra, high-energy conformers from infrared spectra, Rodriguez, O., Lisy, J.M., Journal of Physical Chemistry Letters 2(12), pp. 1444-1448 (2011) |
2009 |
Infrared spectroscopy of gas-phase hydrated K+:18-crown-6 complexes: Evidence for high energy conformer trapping using the argon tagging method, Rodriguez, J.D., Lisy, J.M., International Journal of Mass Spectrometry 283(1-3), pp. 135-139 (2009) |
2008 |
Hydrated alkali-metal cations: Infrared spectroscopy and ab initio calculations of M+(H2O)x=2-5Ar cluster ions for M = Li, Na, K, and Cs, Miller, D.J., Lisy, J.M, Journal of the American Chemical Society 130(46), pp. 15381-15392 (2008) |